Efficacy and Safety of the Angiotensin Receptor Blocker Valsartan in Children With Hypertension Aged 1 to 5 Years

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Efficacy and safety of the Angiotensin receptor blocker valsartan in children with hypertension aged 1 to 5 years.

The efficacy and safety of valsartan were studied in 90 children (mean age: 3.2 years; 60% male; 30% black) with systolic blood pressure (SBP) > or =95th percentile. Nineteen percent received valsartan in addition to previous antihypertensive therapy. Subjects were randomly assigned to low-, medium-, or high-dose valsartan for 2 weeks (phase 1) and then reassigned randomly to placebo or to rema...

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ژورنال

عنوان ژورنال: Hypertension

سال: 2008

ISSN: 0194-911X,1524-4563

DOI: 10.1161/hypertensionaha.108.111054